The Effect of Acute Corticosterone Administration on Retrieval of Remote and Recent Memory in the Rat

نویسندگان

  • Ali Shahbazi Department of Neuroscience Iran University of Medical Sciences
  • Rafie Belali Department of Physiology Iran University of Medical Sciences
چکیده مقاله:

Background and Objective: It is well known that stress and glucocorticoid, modulate memory processing, though the result is completely dependent on the time of stress induction. This study investigated the effect of acute corticosterone administration on memory retrieval of recent and remote memory in a 4 trials/day (low- intensity learning) or 8 trials/ day (high- intensity learning) Morris water maze protocol. Materials and Methods: Sixty four adult male Wistar rats were used in this research study. Corticosterone was injected subcutaneously (3 mg/kg) 30 min before the probe trial test of Morris water maze. Control animals received the vehicle. Results: Acute corticosterone, thirty minutes before probe test led to impairment of memory retrieval phase in recent (p Conclusion: Apparently, learning enhancement was just effective for protecting deleterious effects of corticosterone in recent memory and had no effect on remote memory. Thus, acute stress may impair memory retrieval in a time-dependent manner.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

the effect of taftan pozzolan on the compressive strength of concrete in the environmental conditions of oman sea (chabahar port)

cement is an essential ingredient in the concrete buildings. for production of cement considerable amount of fossil fuel and electrical energy is consumed. on the other hand for generating one tone of portland cement, nearly one ton of carbon dioxide is released. it shows that 7 percent of the total released carbon dioxide in the world relates to the cement industry. considering ecological issu...

the washback effect of discretepoint vs. integrative tests on the retention of content in knowledge tests

در این پایان نامه تاثیر دو نوع تست جزیی نگر و کلی نگر بر به یادسپاری محتوا ارزیابی شده که نتایج نشان دهندهکارایی تستهای کلی نگر بیشتر از سایر آزمونها است

15 صفحه اول

the effect of e-64 on the developmental competence of sheep cocs during in vitro maturation

in the present study, the effect of e-64 at different concentrations (0.5, 1, 5 and 10 µm) added to (1) the ivm medium on oocyte nuclear maturation and developmental competence of ovine oocytes, and (2) to the ivc medium on embryonic development of ovine embryos were investigated.

the effect of learning strategies on the speaking ability of iranian students in the context of language institutes

the effect of learning strategies on the speaking ability of iranian students in the context of language institutes abstract language learning strategies are of the most important factors that help language learners to learn a foreign language and how they can deal with the four language skills specifically speaking skill effectively. acknowledging the great impact of learning strategies...

the effect of translation versus matching words and definitions on retrieval of vocabulary among iranian intermediate efl learners

این تحقیق جهت بررسی تأثیر ترجمه در برابر ایجاد ارتباط بین لغات و ارائه معانی بر بازیابی واژگان در میان زبان آموزان متوسط ایرانی انجام شده است. به این منظور سه گروه کامل از دانش آموزان سطح متوسط که کتاب اینترچنج3 را مطالعه می کردند پس از انجام تست استاندارد مهارت سنجی انتخاب شدند. در ابتدا محقق آنها را به دو گروه آزمایشی و یک گروه کنترل یا شاهد تقسیم نمود و درمرحله بعد از کلیه دانش آموزان در سه ...

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


عنوان ژورنال

دوره 5  شماره 2

صفحات  21- 26

تاریخ انتشار 2017-04-01

با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023